Doing that you could make an engine that will make power up top, but it will be slow to spool the turbo, and not have much power below 4k. The 75mm 2L crank isn't very good for spooling a turbo, but if you want a high revving motor and don't care about torque for driving around town then you could do that.. but you will have to run an even larger turbo, which will spool even later. The car would be gutless under 4500rpm.. not what I consider fun to drive.
I must admit I'm a little confused now. I thought you said you wanted 350hp or more on pump gas? Assuming you mean 350whp, since you can't measure chp.. The Cobb stage 3 setup with a vf39 would be lucky to make 250whp, closer to 230-240whp in reality. That's wayyy below what you stated your power goal to be.
Help what? Rods, pistons, and bearings will have no effect on power, just the amount of power the engine can handle without breaking.