Alpine HU's have been treating me well for 2 decades. I strayed away and bought a Kenwood double-din for my wagon, and I've been disappointed. I'm about to do an upgrade, and I've decided to go with an Alpine single-din. It won't look as integrated, but it'll almost certainly sound better, be more intuitive, integrate nicely with my iPod, and it costs less than half the cost of the monster that you're looking at. (I'm envious that you can afford it...)
I've been happy with the Pioneer car speakers that I've purchased. I don't have a lot of experience with their HU's.
Moving to Cockpit and Cabin.